CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication | Science

2 weeks ago 9
Cell cycle events are coordinated by cyclin-dependent kinases (CDKs) to ensure robust cell division. CDK4/6 and CDK2 regulate the growth 1 (G1) to synthesis (S) phase transition of the cell cycle by responding to mitogen signaling, promoting E2F ...
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